VERRUCOUS CARCINOMA DEFINITION
Verrucous carcinoma is a diffuse, papillary, non-metastasizing, well-differentiated malignant neoplasm of the oral epithelium.
VERRUCOUS CARCINOMA CAUSES:
Verrucous carcinoma commonly occurs in people with tobacco chewing and snuff dipping habits.
Age: The tumors usually affects individuals over 60 years of age.
Sex: Predominantly affects males.
- Clinically verrucous carcinoma presents a slow growing, exophytic, papillary growth, having a white pebbly surface.
- The surface of the lesion is sometimes ‘Warty’ and it shows multiple rauge-like folds with deep clefts in between
- In verrucous carcinoma majority of the lesions are exophytic in nature however, there can be few lesions which are of invasive into the underlying tissue including bone.
- The hyperplastic epithelium often exhibits a papillary surface, being covered by a thick layer of para-keratin
- Massively enlarged, bulb like, acanthotic rete rides are seen which often invaginate into the underlying connective tissue stroma.
- All the bulbous rete-ridges of the epithelium tend to project into the underlying connective tissue at more or less the same level and this is knowing as “pushing margin”
- Formation of epithelial pearls and micro cysts are often seen in verrucous carcinoma
- The basement membrane is almost always intact
VERRUCOUS CARCINOMA DIFFERENTIAL DIAGNOSIS:
- Papillary hyperplasia
- Verrucous leukoplakia
- Pyostomatitis vegetans
- Squamous cell carcinoma
- Chronic hyperplastic candidiasis
- Pseudoepitheliomatous hyperplasia
VERRUCOUS CARCINOMA TREATMENT:
Surgical excision or laser therapy. Prognosis is good