It is a malignant neoplasm developing from the striated muscle cells
Rhabdomyosarcoma are histologically categorized into three variants:
- Embryonal rhabdomyosarcoma
- Alveolar rhabdomyosarcoma
- Pleomorphic rhabdomyosarcoma
These neoplasm may arise either from the existing skelitial muscle cells or may be from the pleuripotential mesenchymal cells of connective tissue
RHABDOMYOSARCOMA CLINICAL FEATURES:
Age: Most of these tumors arise during childhood.
Sex:both sexes are equally affected.
- Rhabdomyosarcoma usually are rapidly growing lesions, which cause swelling, pain and extensive tissue damage
- These Lesions are indurated, fixed and are often ulcerated.
- Tongue and palate are the common sites for these lesions.
- Embryonal rhabdomyosarcoma histologically this variant is characterized by small round cells with monotonous looking hyperchromatic nuclei.
- Alveolar rhabdomyosarcoma histologically it is characterized by round cells, which assume a pattern similar to the lung alveoli.
Surgery, radiotherapy and chemotherapy. All the variant have a poor prognosis.