By Medifit Biologicals

 

RHABDOMYOSARCOMA

RHABDOMYOSARCOMA DEFINITION

It is a malignant neoplasm developing from the striated muscle cells

 

RHABDOMYOSARCOMA TYPE:

Rhabdomyosarcoma are histologically categorized into three variants:

  • Embryonal rhabdomyosarcoma
  • Alveolar rhabdomyosarcoma
  • Pleomorphic rhabdomyosarcoma

 

RHABDOMYOSARCOMA ORIGIN:

These neoplasm may arise either from the existing skelitial muscle cells or may be from the pleuripotential mesenchymal cells of connective tissue

 

RHABDOMYOSARCOMA CLINICAL FEATURES:

Age: Most of these tumors arise during childhood.

Sex:both sexes are equally affected.

 

RHABDOMYOSARCOMA PRESENTATION:

  • Rhabdomyosarcoma usually are rapidly growing lesions, which cause swelling, pain and extensive tissue damage
  • These Lesions are indurated, fixed and are often ulcerated.
  • Tongue and palate are the common sites for these lesions.

 

RHABDOMYOSARCOMA HISTOPATHOLOGY:

  • Embryonal rhabdomyosarcoma histologically this variant is characterized by small round cells with monotonous looking hyperchromatic nuclei.
  • Alveolar rhabdomyosarcoma histologically it is characterized by round cells, which assume a pattern similar to the lung alveoli.

 

RHABDOMYOSARCOMA TREATMENT:

Surgery, radiotherapy and chemotherapy. All the variant have a poor prognosis.

By Medifit Biologicals

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