By Medifit Biologicals

 

RHABDOMYOMA (BENIGN NEOPLASM OF STRIATED MUSCLE)

 

RHABDOMYOMA (BENIGN NEOPLASM OF STRIATED MUSCLE)DEFINATION

Rhabdomyoma are benign neoplasm of striated muscles and these are extremely rare lesions.

 

RHABDOMYOMA (BENIGN NEOPLASM OF STRIATED MUSCLE) CLINICAL FEATURES:

 

Age: Peak age of occurrence is the fifth decade of life. However some cases have been cases have been reported at birth or during infancy.

Sex: The lesion occurs more predominantly among males.

Site: Rhanbdomyomas of the oral cavity are often seen on the tongue and the floor of the mouth some lesions may also develop from the lip, palates, larynx, pharynx and uvula, etc.

 

RHABDOMYOMA (BENIGN NEOPLASM OF STRIATED MUSCLE) PRESENTATION:

  • The neoplasm clinically presents a slow growing, well-circumscribed, painless mass.
  • The lesions are often deep-seated and the overlying tissue appears normal.

 

RHABDOMYOMA (BENIGN NEOPLASM OF STRIATED MUSCLE) HISTOPATHOLOGY:

  • Microscopically Rhabdomyoma appears as sharply outlined, un-encapsulated mass; consisting of large, round or oval striated muscle cells.
  • These neoplastic cells have a granular eosinophilic cytoplasm and are rich in glycogen and glycoprotein.
  • Irregular cross-striations are often seen. The cell nuclei are vesicular.

 

RHABDOMYOMA (BENIGN NEOPLASM OF STRIATED MUSCLE) SPECIAL INVESTIGATION:

The diagnosis of Rhabdomyoma can be confirmed by the electron microscopic demonstration of ‘myofibrils’ in the tumor cells.

 

RHABDOMYOMA (BENIGN NEOPLASM OF STRIATED MUSCLE) DIFFERENTIAL DIAGNOSIS:

  • Leiomyoma
  • Granular cell myoblastoma
  • Giant cell fibroma
  • Neurofibroma

 

 

RHABDOMYOMA (BENIGN NEOPLASM OF STRIATED MUSCLE) TREATMENT:

Surgical Excision is the usually recommended treatment

 

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