By Medifit Biologicals

NEUROGENIC SARCOMA

NEUROGENIC SARCOMA DIFINITION

Neurogenic Sarcoma are malignant neoplasm of perineural fibroblast or schwann cells with a poor prognosis.

 

NEUROGENIC SARCOMA CLINICAL FEATURES:

  • These are rapidly growing, painful, noncompresible exophytic masses which causes paresthesia of the lower lip and expansion of the mandible.
  • Lesions are often indurated and non-movable.
  • Intrabony lesions often cause severe destruction of tissue with mobility of the regional teeth.

 

NEUROGENIC SARCOMA RADIOLOGICAL FEATURES:

Radiologically neurogenic sarcomas may produce a small area of fusiform widening of the interior alveolar canal. However some lesions may even cause large area of bone destruction. Root resorption is uncommon.

 

NEUROGENIC SARCOMA HISTOPATHOLOGY:

  • Histopathology the neoplasm exhibits numerous fascicles of spindle-shaped cells with variable number of mitotic figures
  • The nuclei are often pleomorphic and hyperchromatic
  • The fascicle often exhibits some resemblance to antino-A tissue with palisading nuclei, however, most of these lesions are indistinguishable from fibrosarcoma

 

NEUROGENIC SARCOMA TREATMENT:

Surgery excision, radiotherapy and chemotherapy.

By Medifit Biologicals

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