NEUROGENIC SARCOMA DIFINITION
Neurogenic Sarcoma are malignant neoplasm of perineural fibroblast or schwann cells with a poor prognosis.
NEUROGENIC SARCOMA CLINICAL FEATURES:
- These are rapidly growing, painful, noncompresible exophytic masses which causes paresthesia of the lower lip and expansion of the mandible.
- Lesions are often indurated and non-movable.
- Intrabony lesions often cause severe destruction of tissue with mobility of the regional teeth.
NEUROGENIC SARCOMA RADIOLOGICAL FEATURES:
Radiologically neurogenic sarcomas may produce a small area of fusiform widening of the interior alveolar canal. However some lesions may even cause large area of bone destruction. Root resorption is uncommon.
NEUROGENIC SARCOMA HISTOPATHOLOGY:
- Histopathology the neoplasm exhibits numerous fascicles of spindle-shaped cells with variable number of mitotic figures
- The nuclei are often pleomorphic and hyperchromatic
- The fascicle often exhibits some resemblance to antino-A tissue with palisading nuclei, however, most of these lesions are indistinguishable from fibrosarcoma
NEUROGENIC SARCOMA TREATMENT:
Surgery excision, radiotherapy and chemotherapy.