By Medifit Biologicals

NEUROECTODERMAL TUMOR OF INFANCY

NEUROECTODERMAL TUMOR OF INFANCY DEFINITION

Neuroectodermal tumor of infancy is a benign, pigmented neoplasm of the jawbone, which is derived from the tissue of the primitive neural crest.

 

NEUROECTODERMAL TUMOR OF INFANCY CLINICAL FEATURES:

Age: The lesion occurs mainly in infants before age of 6 months, the usual range of age being 1 to 3 month.

Sex: Both sexes are equally affected.

Site: The neoplasm often arise from the anterior part of maxilla, however, mandible is also sometimes affected (25% cases).

 

NEUROECTODERMAL TUMOR OF INFANCY PRESENTATION:

  • Neuroectodermal tumor of infancy clinically presents a swelling of the jawbone with expansion and distortion of the cortical plates.
  • The swelling often cases elevation of the lip and facial asymmetry.
  • The surface of lesion may show a brown or black pigmentation.

Radiographic Feature:

  • Radiographically Neuroectodermal tumor of infancy often exhibits a well-defined radio-lunceny in the jaw that often resembles a cyst
  • The lesion often causes displacement of the developing tooth buds.

 

NEUROECTODERMAL TUMOR OF INFANCY HISTOPATHOLOGY:

  • The lesion is composed of two types of cells and the nonpigmented cell, which are found within the dense connective tissue stroma.
  • The pigmented cells are large with an open nucleus and a lightly staining cytoplasm, which occasionally contains melanin granules.
  • The nonpigmented cells are small with dark, dense nuclei and a scanty cytoplasm and they often resemble lymphocytes.
  • These Unpigmented cells are often arranged in cluster and are surrounded by the pigmented cells.

 

NEUROECTODERMAL TUMOR OF INFANCY TREATMENT:

Surgical excision with through curettage

By Medifit Biologicals

www.medifitbiologicals.com