NEUROECTODERMAL TUMOR OF INFANCY
NEUROECTODERMAL TUMOR OF INFANCY DEFINITION
Neuroectodermal tumor of infancy is a benign, pigmented neoplasm of the jawbone, which is derived from the tissue of the primitive neural crest.
NEUROECTODERMAL TUMOR OF INFANCY CLINICAL FEATURES:
Age: The lesion occurs mainly in infants before age of 6 months, the usual range of age being 1 to 3 month.
Sex: Both sexes are equally affected.
Site: The neoplasm often arise from the anterior part of maxilla, however, mandible is also sometimes affected (25% cases).
NEUROECTODERMAL TUMOR OF INFANCY PRESENTATION:
- Neuroectodermal tumor of infancy clinically presents a swelling of the jawbone with expansion and distortion of the cortical plates.
- The swelling often cases elevation of the lip and facial asymmetry.
- The surface of lesion may show a brown or black pigmentation.
- Radiographically Neuroectodermal tumor of infancy often exhibits a well-defined radio-lunceny in the jaw that often resembles a cyst
- The lesion often causes displacement of the developing tooth buds.
NEUROECTODERMAL TUMOR OF INFANCY HISTOPATHOLOGY:
- The lesion is composed of two types of cells and the nonpigmented cell, which are found within the dense connective tissue stroma.
- The pigmented cells are large with an open nucleus and a lightly staining cytoplasm, which occasionally contains melanin granules.
- The nonpigmented cells are small with dark, dense nuclei and a scanty cytoplasm and they often resemble lymphocytes.
- These Unpigmented cells are often arranged in cluster and are surrounded by the pigmented cells.
NEUROECTODERMAL TUMOR OF INFANCY TREATMENT:
Surgical excision with through curettage