By Medifit Biologicals

NEURILEMMOMA (SCHWANNOMA)

NEURILEMMOMA (SCHWANNOMA) DEFINATION

Neurilemmoma are benign neoplasms derived from the Schwann cells. These cells are neuro-ectodermal in origin and they envelope the axons of the peripheral nerves in the form of a membrane.

 

NEURILEMMOMA (SCHWANNOMA) CLINICAL FEATURE:

Age: The lesion usually arises before the age of 45years.

Sex: Females are affected more often than males.

Site: Neurilemmoma can occur in relation to both the intracranial and the peripheral nerves.

 

NEURILEMMOMA (SCHWANNOMA) PRESENTATION:

  • Neurilemmoma clinically presents a slow enlarging, well-circumscribed, painless, nodule of varying size.
  • The lesion is smooth, firm, exophytic and often appears as a movable swelling beneath the mucosa, which may be tendered to palpation.
  • Some lesions may grow at a faster pace with pain and paresthesia

 

NEURILEMMOMA (SCHWANNOMA) RADIOGRAPHIC FEATURE:

Radiographically central Neurilemmoma present well-defined, unilocular or multilocular radiolucent areas in the jawbone, with expansion and distortion of the cortical palates.

 

NEURILEMMOMA (SCHWANNOMA) HISTOPATHOLOGY:

  • The neoplasm is well demarcated from the surrounding normal tissue by a true capsule or a pseudo capsule of fibrous connective tissue.
  • The basic cellular constituents of the lesion are the proliferating spindle-shaped, neoplastic Schwann cells, having elongated nuclei
  • These cells are arranged in two distinct patterns which are pathognomonic for the Neurilemmoma

 

NEURILEMMOMA (SCHWANNOMA) DIFFERENTIAL DIAGNOSIS:

  • Neurofibroma
  • Fibroma
  • Fibro epithelial polyp
  • Leiomyoma
  • Peripheral giant cell granuloma

 

NEURILEMMOMA (SCHWANNOMA) TREATMENT:

Surgical Excision.

 

By Medifit Biologicals

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