By Medifit Biologicals

 

KERATOACANTHOMA

 

KERATOACANTHOMA DEFINITION

Keratoacanthoma is a benign endophytic epithelial tissue neoplasm, which commonly occurs in the sun-exposed skin of the face and it usually appears as a circumscribed keratin filled crater.

 

KERATOACANTHOMA CLINICAL FEATURES:

Age: Middle aged adults are frequently affected between the age group of 50 to 70 years.

Sex: Male to female ratio in tumor is about 2:1

Site: Keratoacanthoma commonly develops over the skin surface of lips (both upper and lower lips) near the vermillion border. Beside this, the lesion can also occur on the cheeks nose, eyelids and ears.

 

Presentation:

  • Keratoacanthoma often clinically appears as a small, well- circumscribed, elevated and umbilicated, crater – like lesion, with a central depression
  • The lesion are mostly solitaryalthough multiple Keratoacanthoma can occur.

 

KERATOACANTHOMA DIAGNOSIS/ INVESTIGATION:

Histopathology:

  • The lesion consist of a thick hyperkeratinized covering epithelium with a central zone keratin
  • Pathognomonic nonmalignant feature of this neoplasm can be identified at the margin where, the lesion shows a crater like area, plugged with keratin and is surrounded by hyperplastic normal epithelium

Differential Diagnosis:

  • Basel cell Carcinoma
  • Squamous cell carcinoma

 

KERATOACANTHOMA TREATMENT:

Surgical Excision

 

By Medifit Biologicals

www.medifitbiologicals.com