Hemangiopericytoma are malignant neoplasm arising from the pericytes around the blood vessels.
HEMANGIOPERICYTOMA CLINICAL FEATURES:
Age: The neoplasm can occur at any age, however majority of the lesions arise before age of 50 years.
Sex: Both sexes are affected with almost equal frequency.
Site: Tongue, lips, floor of the mouth, gingiva and jawbones, etc.
- Hemangiopericytoma clinically presents a slow enlarging, painless, well-circumscribed growth.
- It is often firm in consistency and the surface is usually nodular.
- Central jaw lesions may produce large, expansile, painful growths of the jawbone with mobility or exfoliation of the regional teeth.
- There will be multiple number of normal appearing, ‘capillary-like’ tubules lined by a single layer of flattened endothelial cells.
- The capillary-like tubules are bordered on their outer aspect by some densely or loosely packed cells, which are showing plump nuclei and indistinct cytoplasm.
- The demonstration of capillary basement membrane by silver-reticulin stain reveals that these malignant pericytes are present outside the basement membrane and these cells are sharply demarcated from endothelial cells by the ‘peri-endothelial ring’ of reticulin fibers.
HEMANGIOPERICYTOMA DIFFERENTIAL DIAGNOSIS:
- Kaposis sarcoma
- Glomus tumor
Surgical excision is the treatment of choice, the lesion is radio resistant.