By Medifit Biologicals

HEMANGIOPERICYTOMA

HEMANGIOPERICYTOMA DIFINITION

Hemangiopericytoma are malignant neoplasm arising from the pericytes around the blood vessels.

 

HEMANGIOPERICYTOMA CLINICAL FEATURES:

Age: The neoplasm can occur at any age, however majority of the lesions arise before age of 50 years.

Sex: Both sexes are affected with almost equal frequency.

Site: Tongue, lips, floor of the mouth, gingiva and jawbones, etc.

 

HEMANGIOPERICYTOMA PRESENTATION:

  • Hemangiopericytoma clinically presents a slow enlarging, painless, well-circumscribed growth.
  • It is often firm in consistency and the surface is usually nodular.
  • Central jaw lesions may produce large, expansile, painful growths of the jawbone with mobility or exfoliation of the regional teeth.

 

HEMANGIOPERICYTOMA HISTOPATHOLOGY:

  • There will be multiple number of normal appearing, ‘capillary-like’ tubules lined by a single layer of flattened endothelial cells.
  • The capillary-like tubules are bordered on their outer aspect by some densely or loosely packed cells, which are showing plump nuclei and indistinct cytoplasm.
  • The demonstration of capillary basement membrane by silver-reticulin stain reveals that these malignant pericytes are present outside the basement membrane and these cells are sharply demarcated from endothelial cells by the ‘peri-endothelial ring’ of reticulin fibers.

 

HEMANGIOPERICYTOMA DIFFERENTIAL DIAGNOSIS:

  • Hemangioma
  • Kaposis sarcoma
  • Glomus tumor

 

HEMANGIOPERICYTOMA TREATMENT:

Surgical excision is the treatment of choice, the lesion is radio resistant.

 

By Medifit Biologicals

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