Hemangioendothelioma is a malignant angiomatous neoplasm of mesenchymal tissue origin, which is derived from the endothelial cells of the blood vessels or lymphatic vessels.
HEMANGIOENDOTHELIOMA CLINICAL FEATURES:
Age: Hemangioendothelioma are more commonly seen in children and young adults.
Sex: Females are affected more often than males with a ratio of about (2:1).
Sites: Hemangiodothelioma are more commonly found in the skin and the subcutaneous tissues.
Oral lesions are rare and they may arise from the lips, palates, gingiva and tongue, etc.
- Hemangioendothelioma clinically presents a fast enlarging, localized, painful, nodular swelling.
- The lesions often shows surface ulceration, moreover, paresthesia or anesthesia of a affected are is also common.
- Hemangiodothelioma sometimes clinically exhibit hemangioma- like appearance and in such cases the neoplasm appears as flat or slightly raised lesion, with a dark-red or bluish- red surface.
- The central jaw lesion usually produce expansile, destructive growth with swelling, pain and cortical expansion, etc.
- Hemangioendothelioma microscopically presents neoplastic proliferation of malignant endothelial cells with variable degrees of individual cell differentiation.
- The cells are pleomorphic, large, polyhedral.
- An increased abnormal mitosis may be seen.
- The neoplasm is not encapsulated and the cells often tend to invade into the surrounding tissue.
Surgical Excision and Radiotherapy.