By Medifit Biologicals

 

HEMANGIOENDOTHELIOMA

 

HEMANGIOENDOTHELIOMA DIFINITION

Hemangioendothelioma is a malignant angiomatous neoplasm of mesenchymal tissue origin, which is derived from the endothelial cells of the blood vessels or lymphatic vessels.

 

HEMANGIOENDOTHELIOMA CLINICAL FEATURES:

Age: Hemangioendothelioma are more commonly seen in children and young adults.

Sex: Females are affected more often than males with a ratio of about (2:1).

Sites: Hemangiodothelioma are more commonly found in the skin and the subcutaneous tissues.

Oral lesions are rare and they may arise from the lips, palates, gingiva and tongue, etc.

 

HEMANGIOENDOTHELIOMA PRESENTATION:

  • Hemangioendothelioma clinically presents a fast enlarging, localized, painful, nodular swelling.
  • The lesions often shows surface ulceration, moreover, paresthesia or anesthesia of a affected are is also common.
  • Hemangiodothelioma sometimes clinically exhibit hemangioma- like appearance and in such cases the neoplasm appears as flat or slightly raised lesion, with a dark-red or bluish- red surface.
  • The central jaw lesion usually produce expansile, destructive growth with swelling, pain and cortical expansion, etc.

 

HEMANGIOENDOTHELIOMA HISTOPATHOLOGY:

  • Hemangioendothelioma microscopically presents neoplastic proliferation of malignant endothelial cells with variable degrees of individual cell differentiation.
  • The cells are pleomorphic, large, polyhedral.
  • An increased abnormal mitosis may be seen.
  • The neoplasm is not encapsulated and the cells often tend to invade into the surrounding tissue.

 

HEMANGIOENDOTHELIOMA TREATMENT:

Surgical Excision and Radiotherapy.

By Medifit Biologicals

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