By Medifit Biologicals

GIANT-CELL FIBROMA

GIANT-CELL FIBROMA DEFINITION

Giant cell fibromas are distinct neoplastic entitles which arise from the fibrous connective tissues.

 

GIANT-CELL FIBROMA CLINICAL FEATURES:

Age: Most of the Giant cell fibromas develop in the first, second or third decade of life.

Sex: Slightly more prevalent among females.

Site: Maxillary or mandibular gingiva is most frequently affected, beside this tongue, palate and buccal mucosa may also be affected.

 

GIANT-CELL FIBROMA  PRESENTATION:

  • The unique clinical characteristic of the lesion is its pedunculated type of growth.
  • The lesion usually has a papillary or warty surface.
  • Some tumors may present a painless, non-ulcerated and nodular growth.

 

GIANT-CELL FIBROMA HISTOPATHOLOGY:

  • Giant cell fibromas microscopically actively proliferating, numerous, large fibroblast cells with formation of several collagen bundles.
  • Presence of multiple multinucleated giant cells is the hallmark in the histopathology of this lesion.
  • The nuclei within the giant cells are large, hyperchromatic and vesicular. The cytoplasm exhibits prominent dendritic processes and it also contains several melanin granules.

 

GIANT-CELL FIBROMA TREATMENT:

 Surgical excision

Giant cell fibromas are distinct neoplastic entitles which arise from the fibrous connective tissues.

By Medifit Biologicals

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